Hackl, Christina and Schmidt, Katharina M. and Suesal, Caner and Doehler, Bernd and Zidek, Martin and Schlitt, Hans J. (2018) Split liver transplantation: Current developments. WORLD JOURNAL OF GASTROENTEROLOGY, 24 (47). pp. 5312-5321. ISSN 1007-9327, 2219-2840
Full text not available from this repository. (Request a copy)Abstract
In 1988, Rudolf Pichlmayr pioneered split liver transplantation (SLT), enabling the transplantation of one donor liver into two recipients - one pediatric and one adult patient. In the same year, Henri Bismuth and colleagues performed the first full right/full left split procedure with two adult recipients. Both splitting techniques were rapidly adopted within the transplant community. However, a SLT is technically demanding, may cause increased perioperative complications, and may potentially transform an excellent deceased donor organ into two marginal quality grafts. Thus, crucial evaluation of donor organs suitable for splitting and careful screening of potential SLT recipients is warranted. Furthermore, the logistic background of the splitting procedure as well as the organ allocation policy must be adapted to further increase the number and the safety of SLT. Under defined circumstances, in selected patients and at experienced transplant centers, SLT outcomes can be similar to those obtained in full organ LT. Thus, SLT is an important tool to reduce the donor organ shortage and waitlist mortality, especially for pediatric patients and small adults. The present review gives an overview of technical aspects, current developments, and clinical outcomes of SLT.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DONOR LIVER; WEIGHT RATIO; VOLUME; GRAFT; RECIPIENTS; MODEL; FEASIBILITY; MULTICENTER; EXPERIENCE; FORMULA; Liver transplantation; Organ shortage; In situ split; Extended right lobe; Left lateral lobe; Living donor |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 07 Apr 2020 10:00 |
| Last Modified: | 07 Apr 2020 10:00 |
| URI: | https://pred.uni-regensburg.de/id/eprint/13338 |
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