Gschlieber, Andreas and Stifter, Eva and Neumayer, Thomas and Moser, Elisabeth and Papp, Andrea and Pircher, Niklas and Dorner, Guido and Egger, Stefan and Vukojevic, Nenad and Oberacher-Velten, Isabel and Schmidt-Erfurth, Ursula (2018) EFFECT OF PATIENTS' CLINICAL INFORMATION ON THE DIAGNOSIS OF AND DECISION TO TREAT RETINOPATHY OF PREMATURITY. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 38 (11). pp. 2253-2259. ISSN 0275-004X, 1539-2864
Full text not available from this repository. (Request a copy)Abstract
Purpose: To evaluate the effect of patients' clinical information on experts' diagnoses of retinopathy of prematurity (ROP) and decisions to treat. Methods: Seven experts assessed wide-field fundus photographs of eyes of 52 premature infants of <= 30 weeks' gestational age or <= 1,500 g birthweight (BW) for ROP diagnosis (stage, plus disease, and aggressive posterior ROP) and the necessity for treatment for 2 days. On Day 1, they were masked to all patient data. On Day 2, they were given information on gestational age and BW. Results: A significant shift in the experts' ratings toward a less aggressive ROP grading stage (P = 0.006) and less frequent decision for intervention (P = 0.021) was observed after receipt of patients' clinical information. This was truer for heavier/less premature infants (gestational age >= 28 0/7 weeks or BW >= 900 g) than those with very low BWs/high prematurity (gestational age < 24 0/7 weeks or BW < 600 g) (ROP stage P = 0.009 vs. P = 0.399, treatment decision P = 0.022 vs. P = 0.648). Conclusion: These results suggest knowledge of patients' clinical information influences the grading of ROP disease and decision for treatment. Retinopathy of prematurity staging seemed to be set at a lower level and the decision for treatment at a higher threshold for heavier/less premature babies. Our findings may have implications for further refinements in ROP assessment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RISK-FACTORS; INFANTS; REDUCTION; AGREEMENT; birthweight; examiner bias; gestational age; patients' clinical information; retinopathy of prematurity |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Pädiatrische Ophthalmologie, Strabismologie und Ophthalmogenetik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 10 Oct 2019 07:19 |
| Last Modified: | 10 Oct 2019 07:19 |
| URI: | https://pred.uni-regensburg.de/id/eprint/13575 |
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