Toggweiler, Stefan and Cerillo, Alfredo G. and Kim, Won K. and Biaggi, Patric and Lloyd, Clinton and Hilker, Michael and Almagor, Yaron and Cuculi, Florim and Brinkert, Miriam and Kobza, Richard and Muller, Olivier and Ruck, Andreas and Corti, Roberto (2018) Transfemoral Implantation of the Acurate neo for the Treatment of Aortic Regurgitation. JOURNAL OF INVASIVE CARDIOLOGY, 30 (9). pp. 329-333. ISSN 1042-3931, 1557-2501
Full text not available from this repository. (Request a copy)Abstract
Objectives. We report an international experience of transfemoral transcatheter aortic valve replacement (TAVR] using the self-expanding Acurate neo valve (Boston Scientific) in aortic regurgitation. Methods. This series comprises 20 patients with pure aortic regurgitation undergoing transfemoral TAVR with the Acurate neo prosthesis at nine centers in Europe and Israel. Results. Mean age was 79 +/- 8 years and mean STS score was 8.3 +/- 9.3%. Leaflet calcification was none/minimal in 19 patients (95%). Prosthesis size selection was based on perimeter-derived annular diameter, with a tendency to over-size in cases of borderline annuli. One patient required implantation of a second valve. Device success rate was 18/20 (90%). At discharge, aortic regurgitation was none in 14 patients (70%), mild in 5 patients (25%), and moderate in 1 patient (5%). Left ventricular end-diastolic diameter decreased from 58 +/- 7 mm at baseline to 53 +/- 7 mm before discharge (P<.001). At 30-day follow-up, there was no mortality, no stroke, and 3 patients (15%) had received a permanent pacemaker. New York Heart Association class had improved significantly compared to baseline (85% in class I/II compared to 15% at baseline; P<.001). Conclusions. In a selected patient population, transfemoral TAVR using the Acurate neo transcatheter heart valve was successful in treating aortic regurgitation, significantly reduced left ventricular dimensions, and improved clinical symptoms.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | VALVE IMPLANTATION; TRANSCATHETER; REPLACEMENT; aortic regurgitation; degenerative valve; femoral; transcatheter aortic valve implantation; transcatheter aortic valve replacement |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Dec 2019 09:46 |
| Last Modified: | 13 Dec 2019 09:46 |
| URI: | https://pred.uni-regensburg.de/id/eprint/13893 |
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