Jacquemin, Laure and Shekhawat, Giriraj Singh and Van de Heyning, Paul and Mertens, Griet and Fransen, Erik and Van Rompaey, Vincent and Topsakal, Vedat and Moyaert, Julie and Beyers, Jolien and Gilles, Annick (2018) Effects of Electrical Stimulation in Tinnitus Patients: Conventional Versus High-Definition tDCS. NEUROREHABILITATION AND NEURAL REPAIR, 32 (8). pp. 714-723. ISSN 1545-9683, 1552-6844
Full text not available from this repository. (Request a copy)Abstract
Background. Contradictory results have been reported for transcranial direct current stimulation (tDCS) as treatment for tinnitus. The recently developed high-definition tDCS (HD tDCS) uses smaller electrodes to limit the excitation to the desired brain areas. Objective. The current study consisted of a retrospective part and a prospective part, aiming to compare 2 tDCS electrode placements and to explore effects of HD tDCS by matched pairs analyses. Methods. Two groups of 39 patients received tDCS of the dorsolateral prefrontal cortex (DLPFC) or tDCS of the right supraorbital-left temporal area (RSO-LTA). Therapeutic effects were assessed with the tinnitus functional index (TFI), a visual analogue scale (VAS) for tinnitus loudness, and the hyperacusis questionnaire (HQ) filled out at 3 visits: pretherapy, posttherapy, and follow-up. With a new group of patients and in a similar way, the effects of HD tDCS of the right DLPFC were assessed, with the tinnitus questionnaire (TQ) and the hospital anxiety and depression scale (HADS) added. Results. TFI total scores improved significantly after both tDCS and HD tDCS (DLPFC: P < .01; RSO-LTA: P < .01; HD tDCS: P = .05). In 32% of the patients, we observed a clinically significant improvement in TFI. The 2 tDCS groups and the HD tDCS group showed no differences on the evolution of outcomes over time (TFI: P = .16; HQ: P = .85; VAS: P = .20). Conclusions. TDCS and HD tDCS resulted in a clinically significant improvement in TFI in 32% of the patients, with the 3 stimulation positions having similar results. Future research should focus on long-term effects of electrical stimulation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DORSOLATERAL PREFRONTAL CORTEX; DEPRESSION SCALE; HOSPITAL ANXIETY; FUNCTIONAL INDEX; MODULATION; QUESTIONNAIRE; VALIDATION; DUTCH; NEUROMODULATION; SUPPRESSION; tinnitus; neuromodulation; noninvasive brain stimulation; transcranial direct current stimulation (tDCS); high-definition transcranial direct current stimulation (HD tDCS); treatment |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 18 Mar 2020 10:28 |
| Last Modified: | 06 Apr 2020 04:57 |
| URI: | https://pred.uni-regensburg.de/id/eprint/14151 |
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