Keller, Kate E. and Bhattacharya, Sanjoy K. and Borras, Theresa and Brunner, Thomas M. and Chansangpetch, Sunee and Clark, Abbott F. and Dismuke, W. Michael and Du, Yiqin and Elliott, Michael H. and Ethier, C. Ross and Faralli, Jennifer A. and Freddo, Thomas F. and Fuchshofer, Rudolf and Giovingo, Michael and Gong, Haiyan and Gonzalez, Pedro and Huang, Alex and Johnstone, Murray A. and Kaufman, Paul L. and Kelley, Mary J. and Knepper, Paul A. and Kopczynski, Casey C. and Kuchtey, John G. and Kuchtey, Rachel W. and Kuehn, Markus H. and Lieberman, Raquel L. and Lin, Shan C. and Liton, Paloma and Liu, Yutao and Luetjen-Drecoll, Elke and Mao, Weiming and Masis-Solano, Marisse and McDonnell, Fiona and McDowell, Colleen M. and Overby, Darryl R. and Pattabiraman, Padmanabhan P. and Raghunathan, Vijay K. and Rao, P. Vasanth and Rhee, Douglas J. and Chowdhury, Uttio Roy and Russell, Paul and Samples, John R. and Schwartz, Donald and Stubbs, Evan B. and Tamm, Ernst R. and Tan, James C. and Toris, Carol B. and Torrejon, Karen Y. and Vranka, Janice A. and Wirtz, Mary K. and Yorio, Thomas and Zhang, Jie and Zode, Gulab S. and Fautsch, Michael P. and Peters, Donna M. and Acott, Ted S. and Stamer, W. Daniel (2018) Consensus recommendations for trabecular meshwork cell isolation, characterization and culture. EXPERIMENTAL EYE RESEARCH, 171. pp. 164-173. ISSN 0014-4835, 1096-0007
Full text not available from this repository. (Request a copy)Abstract
Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow resistance and thus intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review, we describe the standard procedures used for the isolation of TM cells from several animal species including humans, and the methods used to validate their identity. Having a set of standard practices for TM cells will increase the scientific rigor when used as a model, and enable other researchers to replicate and build upon previous findings.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ALPHA-B-CRYSTALLIN; STEM-CELLS; EXTRACELLULAR-MATRIX; ENDOTHELIAL-CELLS; AQUEOUS-HUMOR; GROWTH-CHARACTERISTICS; CORNEAL ENDOTHELIUM; GENE-EXPRESSION; TISSUE-CULTURE; PRIMATE EYE; Aqueous humor dynamics; Conventional outflow; Glaucoma; Intraocular pressure; Ocular hypertension |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Humananatomie und Embryologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Mar 2020 10:32 |
| Last Modified: | 09 Mar 2020 10:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/14434 |
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