Wiesholler, Lisa M. and Hirsch, Thomas (2018) Strategies for the design of bright upconversion nanoparticles for bioanalytical applications. OPTICAL MATERIALS, 80. pp. 253-264. ISSN 0925-3467, 1873-1252
Full text not available from this repository. (Request a copy)Abstract
In recent years upconversion nanoparticles (UCNPs) received great attention because of their outstanding optical properties. Especially in bioanalytical applications this class of materials can overcome limitations of common probes like high background fluorescence or blinking. Nevertheless, the requirements for UCNPs to be applicable in biological samples, e.g. small size, water-dispersibility, excitation at low power density are in contradiction with the demand of high brightness. Therefore, a lot of attention is payed to the enhancement of the upconversion luminescence. This review discuss the recent trends and strategies to boost the brightness of UCNPs, classified in three main directions: a) improving the efficiency of energy absorption by the sensitizer via coupling to plasmonic or photonic structures or via attachment of ligands for light harvesting; b) minimizing non-radiative deactivation by variations in the architecture of UCNPs; and c) changing the excitation wavelength to get bright particles at low excitation power density for applications in aqueous systems. These strategies are critically reviewed including current limitations as well as future perspectives for the design of efficient UCNPs especially for sensing application in biological samples or cells.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEAR-INFRARED LIGHT; IN-VIVO; UPCONVERTING NANOPARTICLES; CORE/SHELL NANOPARTICLES; EMISSION ENHANCEMENT; GOLD NANOPARTICLES; PHOTONIC CRYSTALS; ENERGY MIGRATION; QUANTUM YIELD; CROSS-SECTION; Upconversion; Nanoparticles; Biosensors; Luminescence; Probes |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Mar 2020 08:40 |
| Last Modified: | 09 Mar 2020 08:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/14447 |
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