Liebig-Hoerl, G. and Puchner, C. and Gerken, M. and Klinkhammer-Schalke, M. and Fuerst, A. (2018) Treatment strategy for early stage rectal cancer (T1 carcinoma). CHIRURG, 89 (5). pp. 358-364. ISSN 0009-4722, 1433-0385
Full text not available from this repository. (Request a copy)Abstract
Backround. A common consensus for the definition for early rectal cancer does not exist. This item is used in cases of histological findings including pTis, pT1 or pT2 tumors. The term early rectal cancer is not mentioned in the German S3 guidelines on colorectal cancer. The pTis tumors are located at the mucosa level of the intestinal wall and they have nearly no tendency to develop metastases but pT2 tumors have a high risk of local metastases; therefore, the term early rectal cancer is not adequate for pT2 tumors. Objective. This focus of this article is exclusively on pT1 rectal cancer. Following the histological definition, pT1 tumors of the rectum are located at the level of the mucosa and submucosa of the intestinal wall. Conclusion. With respect to the nature of the tumor (e.g. size, grading, invasion of lymphatic and/or blood vessels, Kikuchi classification) local methods (endoscopic procedure, surgical techniques) or radical resections are recommended. Tumor budding is of increasing interest and importance. Depending on the severity of the tumor budding classification (bd1-bd3) there is an association with a more frequent occurrence of lymph node metastases and should therefore be taken into consideration in treatment decisions in the future.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LYMPH-NODE METASTASIS; TRANSANAL ENDOSCOPIC MICROSURGERY; LOCAL EXCISION; COLORECTAL-CANCER; RISK; THERAPY; ADENOCARCINOMA; MANAGEMENT; RECURRENCE; SURGERY; T1 rectal cancer; Tumor budding; Kikuchi classification; Transanal microsurgery; Follow-up care |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V. |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Mar 2020 12:22 |
| Last Modified: | 06 Apr 2020 05:19 |
| URI: | https://pred.uni-regensburg.de/id/eprint/14654 |
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