Salzmann, Gian M. and Niemeyer, Philipp and Hochrein, Alfred and Stoddart, Martin J. and Angele, Peter (2018) Articular Cartilage Repair of the Knee in Children and Adolescents. ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE, 6 (3). ISSN 2325-9671
Full text not available from this repository. (Request a copy)Abstract
Articular cartilage predominantly serves a biomechanical function, which begins in utero and further develops during growth and locomotion. With regard to its 2-tissue structure (chondrocytes and matrix), the regenerative potential of hyaline cartilage defects is limited. Children and adolescents are increasingly suffering from articular cartilage and osteochondral deficiencies. Traumatic incidents often result in damage to the joint surfaces, while repetitive microtrauma may cause osteochondritis dissecans. When compared with their adult counterparts, children and adolescents have a greater capacity to regenerate articular cartilage defects. Even so, articular cartilage injuries in this age group may predispose them to premature osteoarthritis. Consequently, surgery is indicated in young patients when conservative measures fail. The operative techniques for articular cartilage injuries traditionally performed in adults may be performed in children, although an individualized approach must be tailored according to patient and defect characteristics. Clear guidelines for defect dimension-associated techniques have not been reported. Knee joint dimensions must be considered and correlated with respect to the cartilage defect size. Particular attention must be given to the subchondral bone, which is frequently affected in children and adolescents. Articular cartilage repair techniques appear to be safe in this cohort of patients, and no differences in complication rates have been reported when compared with adult patients. Particularly, autologous chondrocyte implantation has good biological potential, especially for large-diameter joint surface defects.
| Item Type: | Article |
|---|---|
| Additional Information: | Artikelnummer passt nicht in das vorgesehene Feld, habe ich deshalb weg gelassen /gup |
| Uncontrolled Keywords: | AUTOLOGOUS CHONDROCYTE IMPLANTATION; JUVENILE OSTEOCHONDRITIS-DISSECANS; MESENCHYMAL STEM-CELLS; ACUTE PATELLAR DISLOCATION; SURGICAL-MANAGEMENT; LIGAMENT RECONSTRUCTION; PEDIATRIC POPULATION; TISSUE REGENERATION; CLINICAL-OUTCOMES; OVERUSE INJURIES; cartilage; knee; children; adolescents; osteochondritis dissecans; joint |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Unfallchirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 26 Jun 2020 09:50 |
| Last Modified: | 26 Jun 2020 09:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/14895 |
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