Khoshkish, Shayan and Hohl, Mathias and Linz, Benedikt and Arzt, Michael and Mahfoud, Felix and Baumert, Mathias and Schoepe, Jakob and Boehm, Michael and Linz, Dominik (2018) The association between different features of sleep-disordered breathing and blood pressure: A cross-sectional study. JOURNAL OF CLINICAL HYPERTENSION, 20 (3). pp. 575-581. ISSN 1524-6175, 1751-7176
Full text not available from this repository. (Request a copy)Abstract
Sleep disordered breathing (SDB) is highly prevalent in patients with high blood pressure (BP). Severity of SDB can be evaluated by the number of apneas and hypopneas per hour (AHI) or by measures of hypoxia. The objective of this study was to assess the association between different measures of SDB and BP. In 134 consecutive patients, polygraphy was performed to determine the AHI. Pulse oximetry was used to determine hypoxemic burden (time below 90% oxygen saturation [T90] and hypoxia load [HL], representing the integrated area above the curve of desaturation). AHI did not correlate with systolic and diastolic BP or pulse pressure. In contrast, HL correlated with pulse pressure during the day (P=.01) and night (P=.0034) before and after adjustment for body mass index. The correlation between systolic BP and HL at night disappeared following adjustment for body mass index. This study generates the hypothesis that nocturnal hypoxemic burden may represent a suitable marker of BP pattern and a potential treatment target in hypertensive patients.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | POSITIVE AIRWAY PRESSURE; ARTERIAL STIFFNESS; PULSE PRESSURE; CARDIOVASCULAR RISK; NOCTURNAL HYPOXEMIA; EUROPEAN-SOCIETY; HEART-FAILURE; APNEA; HYPERTENSION; METAANALYSIS; blood pressure; hypertension; hypoxia; pulse pressure; sleep apnea |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 16 Mar 2020 12:47 |
| Last Modified: | 16 Mar 2020 12:47 |
| URI: | https://pred.uni-regensburg.de/id/eprint/14982 |
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