Deep neuromuscular blockade. Benefits and risks

Unterbuchner, C. and Blobner, M. (2018) Deep neuromuscular blockade. Benefits and risks. ANAESTHESIST, 67 (3). pp. 165-176. ISSN 0003-2417, 1432-055X

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Abstract

Neuromuscular blockade (TOF countaEuro<overline>= 0) can improve tracheal intubation and microlaryngeal surgery. It is also frequently used in many surgical fields including both nonlaparoscopic and laparoscopic surgery to improve surgical conditions and to prevent sudden muscle contractions. Currently there is a controversy regarding the need and the clinical benefits of deep neuromuscular blockade for different surgical procedures. Deep neuromuscular relaxation improves laparoscopic surgical space conditions only marginally when using low intra-abdominal pressure. There is no outcome-relevant advantage of low compared to higher intra-abdominal pressures, but worsen the surgical conditions. Postoperative, residual curarisation can be avoided by algorithm-based pharmacological reversing and quantitative neuromuscular monitoring.

Item Type: Article
Uncontrolled Keywords: LOW-PRESSURE PNEUMOPERITONEUM; IMPROVES SURGICAL CONDITIONS; POSTOPERATIVE SHOULDER PAIN; MUSCLE-RELAXANTS; LAPAROSCOPIC SURGERY; TRACHEAL INTUBATION; RESIDUAL PARALYSIS; CORRUGATOR SUPERCILII; POSTTETANIC COUNT; TRAIN-OF-4 RATIO; Deep neuromuscular blockade; Operation conditions; Reversing; Quantitative neuromuscular monitoring; Residual curarisation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 16 Mar 2020 12:54
Last Modified: 16 Mar 2020 12:54
URI: https://pred.uni-regensburg.de/id/eprint/14985

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