Diagnosis, Treatment, and Outcome of Arterioureteral Fistula: The Urologist's Perspective

Heers, Hendrik and Netsch, Christopher and Wilhelm, Konrad and Secker, Armin and Kurtz, Florian and Spachmann, Philipp and Viniol, Simon and Hofmann, Rainer and Hegele, Axel (2018) Diagnosis, Treatment, and Outcome of Arterioureteral Fistula: The Urologist's Perspective. JOURNAL OF ENDOUROLOGY, 32 (3). pp. 245-251. ISSN 0892-7790, 1557-900X

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Abstract

Introduction: Arterioureteral fistula (AUF) is a rare but potentially life-threatening disease that primarily arises as a long-term complication in oncological patients who have permanent ureteral stenting. The incidence is rising. The objective of this study was to outline the risk factors for management and outcome of AUF in a large individual case series. Patients and Methods: Twenty-six AUF cases in 24 patients from six German tertiary referral centers occurring between 2008 and 2016 were identified retrospectively and entered into a dedicated database by using patient notes and out-patient visits. Results: Of 24 patients, 23 had a history of abdominopelvic surgery for oncological disease, 21/24 had undergone radiotherapy, and 23/24 had long-term ureteral stenting. All cases presented with visible hematuria, 11/26 at the time of a stent exchange. Blood transfusions were required in 92.3%, and intravenous inotropes were needed in 46.2%. Of 26 patients, 11 had flank pain. CT angiogram was positive in 35.7%. Angiography and endovascular fistula repair was performed in 88.5%, and the rest received open surgical repair. Mortality was 7.7%. Endovascular treatment was technically successful in 91.3%, and open surgery was successful in 3/4 cases. Recurrent AUF developed in 3/24 patients. Stent-related complications occurred in 15%. Vascular complications were common. Long-term survival was limited due to progression of the underlying malignant disease. Conclusion: AUF results in major hemorrhage and warrants time-efficient diagnosis and treatment. Awareness is key. When AUF is considered, interventional angiography should promptly be performed. Fistula detection can be improved by guidewire manipulation. Pre-interventional CT angiogram may be omitted due to low sensitivity. Endovascular repair with stenting and/or coiling is effective and safe.

Item Type: Article
Uncontrolled Keywords: URETEROARTERIAL FISTULA; ENDOVASCULAR MANAGEMENT; STENT GRAFT; fistula; ureter; oncology; stent graft; upper urinary tract
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Urologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 19 Mar 2020 05:40
Last Modified: 19 Mar 2020 05:40
URI: https://pred.uni-regensburg.de/id/eprint/15057

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