Long-term outcome after the acute respiratory distress syndrome: different from general critical illness?

Bein, Thomas and Weber-Carstens, Steffen and Apfelbacher, Christian (2018) Long-term outcome after the acute respiratory distress syndrome: different from general critical illness? CURRENT OPINION IN CRITICAL CARE, 24 (1). pp. 35-40. ISSN 1070-5295, 1531-7072

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Abstract

Purpose of reviewTo review the current research data on long-term outcome and health-related quality of life in survivors of the acute respiratory distress syndrome (ARDS) and to compare these findings with those from non-ARDS patients surviving critical illness.Recent findingsBetween 6 months and 2 years after discharge from ICU, survivors of ARDS present with substantial impairments of the levels of body function (muscle strength, walking capacity and/or physical activity (physical SF-36 score). In contrast to non-ARDS patients from surgical ICUs, a standardized intensified physical therapy during early course of illness in ARDS patients could not show an improvement of long-term physical function performance. Furthermore, a substantial part of further ARDS patients suffer from depression (26-33%), anxiety (38-44%) or posttraumatic stress disorder (22-24%). In general, the level of functional autonomy and daily life activities was reduced, and in one study, 6 months after ICU-discharge this level was significantly lower in ARDS patients compared with non-ARDS patients. In a recent study, 44% of ARDS survivors were jobless 1 year after critical illness, whereas half of previously employed patients returned to work within 4 months after hospital discharge. General health-related quality of life was significantly reduced compared with a matched population in all studies.SummarySurviving ARDS is associated with a long-term substantial reduction in health-related quality of life and such a reduction does not differ from findings in patients surviving other critical illness. In further research, a special attention should be paid to prevention measures of the post intensive care syndrome' as well as to patient important domains, which might better explain the patient's and families' demands.

Item Type: Article
Uncontrolled Keywords: QUALITY-OF-LIFE; POSTTRAUMATIC-STRESS-DISORDER; RANDOMIZED CONTROLLED-TRIAL; INTENSIVE-CARE-UNIT; SYNDROME SURVIVORS; SYNDROME ARDS; FAILURE; SYMPTOMS; RETURN; WORK; acute respiratory distress syndrome; health-related quality of life; joblessness; muscle weakness; outcome; posttraumatic stress disorder
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Institut für Epidemiologie und Präventivmedizin
Depositing User: Petra Gürster
Date Deposited: 25 Jun 2020 10:06
Last Modified: 25 Jun 2020 10:06
URI: https://pred.uni-regensburg.de/id/eprint/15068

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