Beckmann, Matthias W. and Dittrich, Ralf and Lotz, Laura and van der Ven, Karin and van der Ven, Hans H. and Liebenthron, Jana and Korell, Matthias and Frambach, Torsten and Suetterlin, Marc and Schwab, Roxana and Seitz, Stefan and Mueller, Andreas and von Wolff, Michael and Haeberlin, Felix and Henes, Melanie and Winkler-Crepaz, Katharina and Kruessel, Jan S. and Germeyer, Ariane and Toth, Bettina (2018) Fertility protection: complications of surgery and results of removal and transplantation of ovarian tissue. REPRODUCTIVE BIOMEDICINE ONLINE, 36 (2). pp. 188-196. ISSN 1472-6483, 1472-6491
Full text not available from this repository. (Request a copy)Abstract
Fertility-preserving measures are becoming important for patients receiving oncological treatment. One method involves cryopreservation of ovarian tissue and transplanting it when treatment is completed. We report complications resulting from surgical and fertility medicine, and the results of procedures for the removal and transplantation of ovarian tissue carried out within the FertiProtekt network. A survey using a structured questionnaire was conducted among the FertiProtekt network centres between November 2015 and June 2016. The analysis included surgical techniques used to remove and transplant ovarian tissue, surgical complications and results. Laparoscopic removal and transplantation of ovarian tissue have a low risk of complications. Surgical complications occurred in three of the network's 1373 ovarian tissue removals (n = 1302) and transplantations (n = 71); two complications (0.2%) occurred during removal and one during transplantation. Menstruation resumed in 47 out of 58 women (81%) who underwent ovarian tissue transplantation. Hormonal activity occurred in 63.2% of transplantations with a follow-up of 6 months or over. Sixteen pregnancies occurred in 14 patients, with nine births. The risks and complications of removal and transplantation of ovarian tissue are similar to those of standard laparoscopy. These procedures are becoming standard for fertility protection in cancer patients. (C) 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LIVE BIRTH; FEMALE-PATIENTS; FOLLOW-UP; PRESERVATION; CRYOPRESERVATION; PREGNANCY; AUTOTRANSPLANTATION; CHEMOTHERAPY; THERAPY; DISEASE; cancer; frertility preservation; oncofertility; ovarian tissue; transplantation |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Mar 2020 14:03 |
| Last Modified: | 20 Mar 2020 14:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15155 |
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