Rosenhammer, Bernd and Lausenmeyer, EvaMaria and Mayr, Roman and Burger, Maximilian and Eichelberg, Christian (2018) Holmium Laser Enucleation of the Prostate Provides Similar Incidental Prostate Cancer Detection Rates as Open Prostatectomy: A Matched Pair Analysis. UROLOGIA INTERNATIONALIS, 101 (4). pp. 382-386. ISSN 0042-1138, 1423-0399
Full text not available from this repository. (Request a copy)Abstract
Introduction: Whereas the excellent functional outcomes after Holmium laser enucleation of the prostate (HoLEP) and its equivalency to open prostatectomy (OP) have been studied in detail in the past years, the oncological equivalency has yet to be investigated. Therefore, we conducted a matched pair analysis to evaluate and compare incidental prostate cancer detection rates after HoLEP and OP. Patients and methods: Preoperative patient age, total prostate-specific antigen (PSA), and prostate volume were used as primary matching criteria. Descriptive statistics were used to confirm matching quality. Statistical analyses were performed using Fisher ' s exact test and T-test or Mann-Whitney U-test for dichotomous and continuous variables, respectively. Results: After the matching procedure, 72 out of 145 patients after HoLEP and 72 out of 477 patients after OP were included. Mean patient age (70 vs. 71 years), median prostate volume (106 vs. 107 mL), and median preoperative total PSA (4.32 vs. 4.36 ng/mL) were almost identical. The amount of removed tissue did not differ between HoLEP and OP. Incidental prostate cancer detection rate was similar with 9.7% after HoLEP and 8.3% after OP (p = 1.000). Conclusion: This first matched pair analysis shows that HoLEP does not have a disadvantage regarding cancer detection rate during desobstructive surgery for large prostates. (C) 2018 S. Karger AG, Basel.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSURETHRAL RESECTION; FUNCTIONAL OUTCOMES; RANDOMIZED-TRIAL; FOLLOW-UP; HYPERPLASIA; METAANALYSIS; OBSTRUCTION; Holmium laser enucleation of the prostate; Simple prostatectomy; Incidental prostate cancer; Matched pairs |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Mar 2020 08:06 |
| Last Modified: | 20 Mar 2020 08:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15294 |
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