Masis-Calvo, Marianela and Schmidtner, Anna K. and Oliveira, Vinicius E. de Moura and Grossmann, Cindy P. and de Jong, Trynke R. and Neumann, Inga D. (2018) Animal models of social stress: the dark side of social interactions. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS, 21 (5). pp. 417-432. ISSN 1025-3890, 1607-8888
Full text not available from this repository. (Request a copy)Abstract
Social stress occurs in all social species, including humans, and shape both mental health and future interactions with conspecifics. Animal models of social stress are used to unravel the precise role of the main stress system - the HPA axis - on the one hand, and the social behavior network on the other, as these are intricately interwoven. The present review aims to summarize the insights gained from three highly useful and clinically relevant animal models of psychosocial stress: the resident-intruder (RI) test, the chronic subordinate colony housing (CSC), and the social fear conditioning (SFC). Each model brings its own focus: the role of the HPA axis in shaping acute social confrontations (RI test), the physiological and behavioral impairments resulting from chronic exposure to negative social experiences (CSC), and the neurobiology underlying social fear and its effects on future social interactions (SFC). Moreover, these models are discussed with special attention to the HPA axis and the neuropeptides vasopressin and oxytocin, which are important messengers in the stress system, in emotion regulation, as well as in the social behavior network. It appears that both nonapeptides balance the relative strength of the stress response, and simultaneously predispose the animal to positive or negative social interactions.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHRONIC PSYCHOSOCIAL STRESS; PITUITARY-ADRENAL AXIS; EARLY-LIFE STRESS; INDUCED ABNORMAL AGGRESSION; OXYTOCIN RECEPTOR-BINDING; INTIMATE PARTNER VIOLENCE; MALE GOLDEN-HAMSTERS; MALE-RATS; BRAIN OXYTOCIN; HYPOTHALAMIC VASOPRESSIN; Social stress; aggression; chronic subordinate colony housing; social fear; oxytocin; vasopressin |
| Subjects: | 500 Science > 570 Life sciences 500 Science > 590 Zoological sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 25 Jun 2020 05:43 |
| Last Modified: | 25 Jun 2020 05:43 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15309 |
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