Kandulski, Arne and Moleda, Lukas and Mueller-Schilling, Martina (2018) Diagnostic Investigations of Gastroesophageal Reflux Disease: Who and When to Refer and for What Test? VISCERAL MEDICINE, 34 (2). pp. 97-100. ISSN 2297-4725, 2297-475X
Full text not available from this repository. (Request a copy)Abstract
Background: Due to the high prevalence and incidence of patients with gastroesophageal reflux disease (GERD), the diagnostic workup of patients with symptoms of GERD needs to be balanced between empiric antisecretory therapy and further functional assessment including endoscopy and reflux monitoring. Methods: This article is based on a literature review (PubMed, Medline) using the terms 'gastroesophageal reflux disease' or 'GERD' and 'diagnosis', 'therapy', or 'PPI' with special and critical analysis of the current 'Porto' consensus report. Results and Conclusions: Further diagnostics are mandatory in case of alarm symptoms as well as atypical or persistent symptoms under adequate therapy with proton pump inhibitors (PPI). In general, the clinical situation needs to be clarified before sending the patients for reflux monitoring. The question is not only when and whom to test but also how to test: on or off PPI therapy, pH-metry, or combined pH-impedance analysis. These questions have been defined in a recent consensus report of an international panel of experts and are further discussed in this article. (C) 2018 S. Karger GmbH, Freiburg.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BASE-LINE IMPEDANCE; DILATED INTERCELLULAR SPACES; FUNCTIONAL HEARTBURN; ESOPHAGEAL DISORDERS; EROSIVE ESOPHAGITIS; OMEPRAZOLE TEST; GERD; MANAGEMENT; CONSENSUS; EXPOSURE; Gastroesophageal reflux disease; pH-metry; Diagnostics; Therapy; Proton pump inhibitors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Petra Gürster |
| Date Deposited: | 25 Jun 2020 05:20 |
| Last Modified: | 25 Jun 2020 05:20 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15394 |
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