Sex Differences in the Prevalence and Modulators of Sleep-Disordered Breathing in Outpatients with Type 2 Diabetes

Kroner, T. and Arzt, M. and Rheinberger, M. and Gorski, M. and Heid, I. M. and Boeger, C. A. and Stadler, S. (2018) Sex Differences in the Prevalence and Modulators of Sleep-Disordered Breathing in Outpatients with Type 2 Diabetes. JOURNAL OF DIABETES RESEARCH: 7617524. ISSN 2314-6745, 2314-6753

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Abstract

In patients with type 2 diabetes, sleep-disordered breathing is a widespread cause of deteriorated quality of life. However, robust prevalence estimates for sleep-disordered breathing in patients with type 2 diabetes are limited due to scarce data. We investigated sex differences in sleep-disordered breathing prevalence and its modulators in the DIACORE SDB substudy, a sample of outpatient type 2 diabetes. 721 participants were tested for sleep-disordered breathing using a two-channel sleep apnoea monitoring device. Patients were stratified according to the severity of sleep-disordered breathing, defined as an apnoea-hypopnoea index < 15, >= 15 to 29, and >= 30 events per hour as no/mild, moderate, and severe sleep-disordered breathing, respectively. In the 679 analysed patients (39% women, age 66 +/- 9 years, body mass index 31.0 +/- 5.4 kg/m(2)), the prevalence of sleep-disordered breathing was 34%. The prevalence of sleep-disordered breathing was higher in men than in women (41% versus 22%, p < 0.001) and increased with age (15%, 21%, and 30% in women and 35%, 40%, and 47% in men in those aged 18-59, 60-69, or >= 70, respectively; age trend p = 0.064 in women and p = 0.15 in men). In linear regression analysis, age, BMI, and waist-hip ratio were associated with apnoea-hypopnoea index. Modulators for higher apnoea-hypopnoea index seem to be similar in men and women.

Item Type: Article
Uncontrolled Keywords: POSITIVE AIRWAY PRESSURE; APNEA; MELLITUS; EPIDEMIOLOGY; VALIDATION; CPAP;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 20 Mar 2020 10:56
Last Modified: 20 Mar 2020 10:56
URI: https://pred.uni-regensburg.de/id/eprint/15397

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