Papathemelis, Thomas and Jablonski, Evi and Scharl, Anton and Hauzenberger, Tanja and Gerken, Michael and Klinkhammer-Schalke, Monika and Hipp, Matthias and Scharl, Sophia (2018) Sentinel Lymph Node Biopsy in Breast Cancer Patients by Means of Indocyanine Green Using the Karl Storz VITOM (R) Fluorescence Camera. BIOMED RESEARCH INTERNATIONAL: 6251468. ISSN 2314-6133, 2314-6141
Full text not available from this repository. (Request a copy)Abstract
Currently, the use of radioisotope and blue dye for sentinel lymph node biopsy (SLNB) for axillary staging in breast cancer is common. Recently, indocyanine green (ICG) has been proposed as an alternative sentinel lymph node (SLN) tracking agent. We evaluated the clinical value of ICG as an additional tracer in combination with Technetium(99m) and as an alternative to Technetium(99m) for the identification of SLN in 104 breast cancer patients. 21 patients had at least 1 histologically tumor-positive SLN. All 21 patients were detected by ICG; in one of these 21 sentinel-positive patients, Technetium(99m) was unable to identify lymph node involvement. Our results show that ICG is as effective as the radioisotope for SLNB. In addition, as a near-infrared dye, it has the advantages of real-time visualization, lower cost, and wider availability, since no radioactive material needs to be handled.
Item Type: | Article |
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Uncontrolled Keywords: | BLUE-DYE; NEOADJUVANT CHEMOTHERAPY; SURGERY; BENEFIT; TRIAL; RADIOISOTOPE; METAANALYSIS; CARCINOMA; UPDATE; LIFE; |
Subjects: | 600 Technology > 610 Medical sciences Medicine |
Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V. |
Depositing User: | Dr. Gernot Deinzer |
Date Deposited: | 20 Mar 2020 11:47 |
Last Modified: | 20 Mar 2020 11:47 |
URI: | https://pred.uni-regensburg.de/id/eprint/15408 |
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