Morsczeck, Christian and Reichert, Torsten E. (2018) Dental stem cells in tooth regeneration and repair in the future. EXPERT OPINION ON BIOLOGICAL THERAPY, 18 (2). pp. 187-196. ISSN 1471-2598, 1744-7682
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Introduction: Human dental stem cells can be obtained from postnatal teeth, extracted wisdom teeth or exfoliated deciduous teeth. Due to their differentiation potential, these mesenchymal stem cells are promising for tooth repair. Therefore, the development of dental tissue regeneration represents a suitable but challenging, target for dental stem cell therapies. Areas covered: In this review, the authors provide an overview of human dental stem cells and their properties for regeneration medicine. Numerous preclinical studies have shown that dental stem cells improve bone augmentation and healing of periodontal diseases. Clinical trials are ongoing to validate the clinical feasibility of these approaches. Dental stem cells are also important for basic research. Expert opinion: Dental stem cells offer numerous advantages for tooth repair and regeneration. Data obtained from different studies are encouraging. In the next few years, investigations on dental stem cells in basic research, pre-clinical research and clinical studies will pave the way to optimizing patient-tailored treatments for repair and regeneration of dental tissues.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SUPPORTS OSTEOGENIC DIFFERENTIATION; FOLLICLE CELLS; IN-VITRO; APICAL PAPILLA; BONE TISSUE; REMESTEMCEL-L; IMMUNOMODULATORY PROPERTIES; PULP REGENERATION; PROGENITOR CELLS; PRECURSOR CELLS; Dental stem cells; tissue engineering; periodontitis; endodontics; bone regeneration; dental implants |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 23 Jun 2020 12:38 |
| Last Modified: | 23 Jun 2020 12:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15452 |
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