Schroeder, Josef A. and Siegmund, Heiko I. and Roesch, Wolfgang and Hadziselimovic, Faruk and Hofstaedter, Ferdinand (2013) Male Infertility: Assessment of Juvenile Testicular Dysfunction and Risk for Malignancy in Cryptorchid Boys Based on Resin Section Evaluation. ULTRASTRUCTURAL PATHOLOGY, 37 (5). pp. 373-377. ISSN 0191-3123, 1521-0758
Full text not available from this repository. (Request a copy)Abstract
Infertility is sometimes more a man's problem than a woman's, failure of one or both of the testes to descend (cryptorchidism) being the most frequent genital malformation in boys. Untreated, the undescended testis impairs germ cell development and significantly reduces adult fertility. A-dark spermatogonia are the stem cells for all future spermatozoa, and their depletion can be reliably estimated in resin semithin sections. Additionally, there is an increased risk of testicular preneoplasia in the form of carcinoma in situ (CIS) cells. The authors report how the pathologic biopsy examination of juvenile cryptorchid testes can assess infertility and malignancy risk.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CARCINOMA IN-SITU; GERM-CELL TUMORS; SPERMATOGONIA; DIAGNOSIS; TESTIS; ORCHIDOPEXY; A-dark spermatogonia; carcinoma in situ (CIS); cryptorchidism; male infertility; semithin section; testicular germ cell tumor; testicular intraepithelial neoplasia (TIN) |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Mar 2020 10:20 |
| Last Modified: | 31 Mar 2020 10:20 |
| URI: | https://pred.uni-regensburg.de/id/eprint/15994 |
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