Delayed-onset Ureteral Obstruction After Endoscopic Dextranomer/Hyaluronic Acid Copolymer (Deflux) Injection for Treatment of Vesicoureteral Reflux in Children: A Case Series

Rubenwolf, Peter C. and Ebert, Anne-Karoline and Ruemmele, Petra and Roesch, Wolfgang H. (2013) Delayed-onset Ureteral Obstruction After Endoscopic Dextranomer/Hyaluronic Acid Copolymer (Deflux) Injection for Treatment of Vesicoureteral Reflux in Children: A Case Series. UROLOGY, 81 (3). pp. 659-662. ISSN 0090-4295,

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Abstract

We report 4 patients with upper urinary tract (UUT) obstruction requiring ureteric reimplantation at 1, 7, 28, and 63 months after dextranomer/hyaluronic acid copolymer (Dx/HA) injection for vesicoureteric reflux. Histopathologic evaluation of ureteric segments revealed extensive foreign body formation in all cases. We conclude that UUT obstruction is a rare but serious complication after Dx/HA injection that can occur even years after surgery. The incidence of delayed-onset UUT obstruction may be higher than previously noted. Long-term follow-up and a critical reappraisal of the method are needed to assess the late sequelae of Dx/HA injection therapy for vesicoureteric reflux. UROLOGY 81: 659-662, 2013. (c) 2013 Elsevier Inc.

Item Type: Article
Uncontrolled Keywords: ;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Kinder- und Jugendmedizin
Medicine > Lehrstuhl für Pathologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Apr 2020 04:50
Last Modified: 24 Apr 2020 04:50
URI: https://pred.uni-regensburg.de/id/eprint/17088

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