Role of estrogen receptor beta in gynecological cancer

Haering, Julia and Schueler, Susanne and Lattrich, Claus and Ortmann, Olaf and Treeck, Oliver (2012) Role of estrogen receptor beta in gynecological cancer. GYNECOLOGIC ONCOLOGY, 127 (3). pp. 673-676. ISSN 0090-8258, 1095-6859

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Abstract

Estrogen receptor beta is expressed in normal and neoplastic ovarian and endometrial tissues. Recent studies indicate that levels of this receptor decline in ovarian tumorigenesis, like in breast or prostate cancer. Furthermore, ER beta expression has been associated with good prognosis in ovarian cancer. In contrast, previous studies on the role of this receptor in endometrial cancer suggested that ER beta might play different roles in the carcinogenesis of the ovary and endometrium. Besides its possible role as a prognostic factor, ER beta might be a potential target for the treatment of ovarian and endometrial cancer. (C) 2012 Elsevier Inc. All rights reserved.

Item Type: Article
Uncontrolled Keywords: ALPHA ER-ALPHA; MESSENGER-RNA EXPRESSION; BREAST-CANCER; OVARIAN-CANCER; ENDOMETRIAL CANCER; DIFFERENTIAL EXPRESSION; DNA METHYLATION; PROGNOSTIC-SIGNIFICANCE; CYTOPLASMIC EXPRESSION; PROGESTERONE-RECEPTORS; Ovarian cancer; Endometrial cancer; Estrogen receptor beta
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde)
Depositing User: Petra Gürster
Date Deposited: 27 May 2020 05:42
Last Modified: 27 May 2020 05:42
URI: https://pred.uni-regensburg.de/id/eprint/17684

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