Extracorporeal Membrane Oxygenation by Single-Vessel Access in Adults: Advantages and Limitations

Camboni, Daniele and Philipp, Alois and Lubnow, Matthias and Bein, Thomas and Zausig, York and Hilker, Michael and Floerchinger, Bernhard and Rupprecht, Leopold and Keyser, Andreas and Kobuch, Reinhard and Lunz, Dirk and Schopka, Simon and Haneya, Assad and Schmid, Christof and Mueller, Thomas (2012) Extracorporeal Membrane Oxygenation by Single-Vessel Access in Adults: Advantages and Limitations. ASAIO JOURNAL, 58 (6). pp. 616-621. ISSN 1058-2916,

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Abstract

Veno-venous extracorporeal membrane oxygenation (vvECMO) conventionally requires the cannulation of two vessels. Here we report our initial experience with the "Wang-Zwische" (WZ) double-lumen cannula. In a group of n = 36 patients single venous cannulation for vvECMO was performed. A retrospective analysis was executed. A comparison of flow characteristics to standard two-vessel cannulation was performed. Mean age of the patient population was 48 +/- 15 years (body mass index [BMI] 32 +/- 13 kg/m(2)). In n = 32 patients (89%) the cannula was implanted percutaneously under echo or fluoroscopic guidance in less than 30 minutes. Nine patients were partially mobilized on extracorporeal membrane oxygenation (ECMO) support. Oxygenation (partial arterial oxygen tension [PaO2]/fraction of inspired oxygen [FiO(2)]) improved significantly in all patients from 66 mm Hg (interquartile range [IQR] 58-87 mm Hg) before ECMO to 117 mm Hg (IQR 95-195 mm Hg, p = 0.001) after 24 hours. In seven patients (19%) nonfatal adverse events occurred, including three dislocations, two partial cannula thrombosis, one ventricular perforation, and one retroperitoneal hemorrhage. The negative pressures for drainage at a flow of 2.5 L/min were significantly lower in a standard (S) two-vessel approach compared with a WZ approach (S: -9 mm Hg; IQR -3 to -24 mm Hg, vs. WZ: -23 mm Hg; IQR -4 to -40 mm Hg; p = 0.04). The WZ cannula offers sufficient gas exchange in addition to certain advantages over standard cannulation, including facilitated cannulation in selected patients and improved mobilization. ASAIO Journal 2012;58:616-621.

Item Type: Article
Uncontrolled Keywords: DOUBLE-LUMEN CANNULA; LUNG TRANSPLANTATION; LIFE-SUPPORT; PERCUTANEOUS CANNULATION; FAILURE; BRIDGE; ECMO; respiratory support; canulation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 04 May 2020 10:17
Last Modified: 04 May 2020 10:17
URI: https://pred.uni-regensburg.de/id/eprint/17871

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