Woodruff, Maria A. and Lange, Claudia and Reichert, Johannes and Berner, Arne and Chen, Fulen and Fratzl, Peter and Schantz, Jan-Thorsten and Hutmacher, Dietmar W. (2012) Bone tissue engineering: from bench to bedside. MATERIALS TODAY, 15 (10). pp. 430-435. ISSN 1369-7021
Full text not available from this repository. (Request a copy)Abstract
The drive to develop bone grafts for the filling of major gaps in the skeletal structure has led to a major research thrust towards developing biomaterials for bone engineering. Unfortunately, from a clinical perspective, the promise of bone tissue engineering which was so vibrant a decade ago has so far failed to deliver the anticipated results of becoming a routine therapeutic application in reconstructive surgery. Here we describe our bench to bedside concept, the first clinical results and a detailed analysis of long-term bone regeneration studies in preclinical animal models, exploiting methods of micro- and nano analysis of biodegradable composite scaffolds.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ANIMAL-MODELS; TRICALCIUM PHOSPHATE; GROWTH-FACTORS; SCAFFOLDS; POLYCAPROLACTONE; DEFECTS; RHBMP-2; BIOREACTOR; CARTILAGE; IMPLANT; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Unfallchirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 25 May 2020 10:14 |
| Last Modified: | 25 May 2020 10:14 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18008 |
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