Lange, Klaus W. and Lange, Katharina M. and Hauser, Joachim and Tucha, Lara and Tucha, Oliver (2012) Circadian rhythms in obsessive-compulsive disorder. JOURNAL OF NEURAL TRANSMISSION, 119 (10). pp. 1077-1083. ISSN 0300-9564, 1435-1463
Full text not available from this repository. (Request a copy)Abstract
The etiopathology and neurobiology of obsessive-compulsive disorder (OCD) are not fully understood. As for altered circadian rhythms associated with OCD, hormonal dysregulation and a delayed sleep phase have come into the focus of research. The novel antidepressant agomelatine is able to resynchronize circadian rhythms and the augmentative administration of this compound has been shown to be of benefit in some OCD patients who are refractory to common forms of pharmacotherapy. Adjunctive chronotherapy might also enhance the outcome in treatment-refractory OCD. The present review summarises the findings regarding circadian abnormalities in OCD.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DEXAMETHASONE-SUPPRESSION TEST; CORTICOTROPIN-RELEASING-FACTOR; DELAYED SLEEP PHASE; GABA-A RECEPTOR; NEUROACTIVE STEROIDS; CEREBROSPINAL-FLUID; TOURETTES-SYNDROME; SUCCESSFUL AUGMENTATION; FLUOXETINE TREATMENT; ANXIETY DISORDERS; Obsessive-compulsive disorder (OCD); Circadian rhythm; Hormone dysregulation; Delayed sleep phase; Agomelatine; Chronotherapy |
| Subjects: | 100 Philosophy & psychology > 150 Psychology |
| Divisions: | Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange |
| Depositing User: | Petra Gürster |
| Date Deposited: | 27 May 2020 05:36 |
| Last Modified: | 27 May 2020 05:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18052 |
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