Wound healing after radiation therapy: Review of the literature

Haubner, Frank and Ohmann, Elisabeth and Pohl, Fabian and Strutz, Juergen and Gassner, Holger G. (2012) Wound healing after radiation therapy: Review of the literature. RADIATION ONCOLOGY, 7: 162. ISSN 1748-717X

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Abstract

Radiation therapy is an established modality in the treatment of head and neck cancer patients. Compromised wound healing in irradiated tissues is a common and challenging clinical problem. The pathophysiology and underlying cellular mechanisms including the complex interaction of cytokines and growth factors are still not understood completely. In this review, the current state of research regarding the pathomechanisms of compromised wound healing in irradiated tissues is presented. Current and possible future treatment strategies are critically reviewed.

Item Type: Article
Uncontrolled Keywords: COLONY-STIMULATING FACTOR; GROWTH FACTOR-BB; HYPERBARIC-OXYGEN; STEM-CELLS; TGF-BETA; DERMAL FIBROBLASTS; IRRADIATED SKIN; SOFT-TISSUE; MATRIX METALLOPROTEINASES; CLINICAL-APPLICATIONS; Wound healing; Radiation therapy
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Medicine > Lehrstuhl für Strahlentherapie
Depositing User: Petra Gürster
Date Deposited: 25 May 2020 09:37
Last Modified: 25 May 2020 09:37
URI: https://pred.uni-regensburg.de/id/eprint/18097

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