Gore, Sangram and Baskaran, Sundarababu and Koenig, Burkhard (2012) Fischer Indole Synthesis in Low Melting Mixtures. ORGANIC LETTERS, 14 (17). pp. 4568-4571. ISSN 1523-7060,
Full text not available from this repository. (Request a copy)Abstract
Functionalized indoles are synthezised under mild conditions in a tartaric acid-dimethylurea melt. The melt serves as the solvent and as the catalyst. Under these reaction conditions, sensitive functional groups such as N-Boc, N-Cbz, or azides are stable, and indolenines are obtained regioselectively in excellent yields. The practical use of the method is demonstrated in the synthesis of the hormone melatonin.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | UREA-SALT MIXTURES; IONIC LIQUIDS; ORGANIC-SYNTHESIS; ENOL ETHERS; SOLVENTS; CATALYSIS; REARRANGEMENT; DERIVATIVES; SYSTEM; GREEN; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 May 2020 08:22 |
| Last Modified: | 06 May 2020 08:22 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18123 |
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