A lanostane aldehyde from Momordica charantia

Panlilio, Bella G. and Macabeo, Allan Patrick G. and Knorn, Matthias and Kohls, Paul and Richomme, Pascal and Kouam, Simeon Fogue and Gehle, Dietmar and Krohn, Karsten and Franzblau, Scott G. and Zhang, Qingwen and Aguinaldo, Ma Alicia M. (2012) A lanostane aldehyde from Momordica charantia. PHYTOCHEMISTRY LETTERS, 5 (3). pp. 682-684. ISSN 1874-3900,

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Abstract

A new lanostane aldehyde, charantal (1), was isolated from the ethanolic leaf extract of Momordica charantia together with the known compound, 2,4-bis(2-phenylpropan-2-yl)phenol (2). The structure of compound 1 was elucidated by extensive 1D and 2D NMR and MS experiments. Compound 2 displayed a moderately strong antitubercular activity against Mycobacterium tuberculosis H(37)Rv (MIC = 14 mu g/mL) according to the MABA susceptibility assay. (C) 2012 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

Item Type: Article
Uncontrolled Keywords: MYCOBACTERIUM-TUBERCULOSIS H(37)RV; ALSTONIA-SCHOLARIS; BLETILLA-STRIATA; INDOLE ALKALOIDS; ANTIOXIDANT; TRITERPENES; EXTRACTS; Momordica charantia; Lanostane aldehyde; Charantal; 2,4-Bis(dimethylbenzyl)phenol; Antitubercular
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie
Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 May 2020 05:19
Last Modified: 07 May 2020 05:19
URI: https://pred.uni-regensburg.de/id/eprint/18255

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