Kurtz, Armin (2012) Renal connexins and blood pressure. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1818 (8). pp. 1903-1908. ISSN 0005-2736
Full text not available from this repository. (Request a copy)Abstract
The kidneys are centrally involved in the regulation of blood pressure. Kidney function requires the coordinated actions of a number of different vascular and tubular cell types in the renal vasculature and in the renal tubular system. The intrarenal coordination of these actions is not well understood. Since gap junctions have been identified in the kidneys, possible pathways involved :in this context could be direct intercellular communication via gap junctions or via connexin hemichannels. In this context nine different connexins have been found to be expressed in the kidney, either localized to the vasculature or to the tubular system. Evidence is arising that malfunctions of certain connexins have an impact on the capability of the kidney to maintain blood pressure homeostasis. Findings reported in this context will be outlined and discussed in this review. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and characteristics. (C) 2011 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RENIN-PRODUCING CELLS; GAP JUNCTION PROTEIN; MOLECULAR-CLONING; INTERCELLULAR COMMUNICATION; JUXTAGLOMERULAR APPARATUS; TUBULOGLOMERULAR FEEDBACK; ENDOTHELIAL-CELLS; MESSENGER-RNA; CALCIUM WAVE; DIETARY SALT; Sodium resorption; Cx30; Renin-angiotensin-system; Cx40; Hypertension; Cx40A96S mutation |
| Subjects: | 500 Science > 540 Chemistry & allied sciences 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz |
| Depositing User: | Petra Gürster |
| Date Deposited: | 18 May 2020 06:59 |
| Last Modified: | 18 May 2020 06:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18417 |
Actions (login required)
 |
View Item |
