Dulla, Balakrishna and Wan, Baojie and Franzblau, Scott G. and Kapavarapu, Ravikumar and Reiser, Oliver and Iqbal, Javed and Pal, Manojit (2012) Construction and functionalization of fused pyridine ring leading to novel compounds as potential antitubercular agents. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22 (14). pp. 4629-4635. ISSN 0960-894X,
Full text not available from this repository. (Request a copy)Abstract
A series of fused and functionalized pyridine derivatives were designed, synthesized and tested for their potential antitubercular properties. All these novel compounds were prepared by using multistep methods involving the construction of pyridine ring as a key synthetic step. Some of these compounds were found to be interesting when tested for their antitubercular properties in vitro and one of them appeared as an attractive and potential antitubercular agent. (C) 2012 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DRUG-RESISTANT TUBERCULOSIS; MYCOBACTERIUM-TUBERCULOSIS; SHIKIMATE DEHYDROGENASE; MULTIDRUG-RESISTANT; INHIBITORS; LIGANDS; TB; Pyridine; Quinoline; X-ray; In vitro; Tuberculosis |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 11 May 2020 05:33 |
| Last Modified: | 11 May 2020 05:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18440 |
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