Topical Delivery of Steroids in Inflammatory Bowel Disease

Girlich, C. and Schoelmerich, J. (2012) Topical Delivery of Steroids in Inflammatory Bowel Disease. CURRENT DRUG DELIVERY, 9 (4). pp. 345-349. ISSN 1567-2018

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Abstract

Crohn's disease (CD) and ulcerative colitis (UC) represent two similar but probably not uniform entities of inflammatory bowel disease (IBD). Since up to now no curative treatment is available the therapeutic goal in active IBD is elimination or at least alleviation of symptoms and maintenance of remission. Glucocorticoids have been successfully used in the treatment of symptoms and inflammation. Due to the minor systemic side effects a topical drug delivery targeting the active substances directly to the inflamed sites would be the favorable administration. In this review the use of topical corticosteroids is discussed, based on a short description of their pharmacological properties.

Item Type: Article
Uncontrolled Keywords: ACTIVE CROHNS-DISEASE; DISTAL ULCERATIVE-COLITIS; ILEAL RELEASE CAPSULES; BECLOMETHASONE DIPROPIONATE; ORAL BUDESONIDE; 5-AMINOSALICYLIC ACID; MAINTENANCE TREATMENT; RETENTION ENEMAS; CONTROLLED-TRIAL; DOUBLE-BLIND; Steroids; inflammatory bowel disease
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin I
Depositing User: Petra Gürster
Date Deposited: 18 May 2020 06:57
Last Modified: 18 May 2020 06:57
URI: https://pred.uni-regensburg.de/id/eprint/18466

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