Schoenfeldt-Lecuona, C. and Cardenas-Morales, L. and Moreno-Aguirre, A. and Dorn, K. and Langguth, B. and Bruehl, A. B. and Kammer, T. and Herwig, U. (2012) Effect of 1 Hz Repetitive Transcranial Magnetic Stimulation Over the Auditory Cortex on Audiometry and Otoacustic Emissions. BRAIN TOPOGRAPHY, 25 (3). pp. 241-247. ISSN 0896-0267, 1573-6792
Full text not available from this repository. (Request a copy)Abstract
Repetitive transcranial magnetic stimulation (rTMS) at low frequencies (a parts per thousand currency sign1 Hz) delivered to the primary motor cortex for 15 min or longer has been shown to reduce motor cortex excitability. Over the visual cortex, 1 Hz rTMS led to increased phosphene thresholds and over the auditory cortex rTMS reduced auditory evoked potentials. rTMS above the auditory or temporo-parietal cortex has also been reported to reduce the severity of auditory hallucinations and the perception of tinnitus. However, possible unwanted effects on hearing function have not yet been investigated systematically. 12 right-handed normal hearing subjects (5 male, mean age 28.2 +/- A 4.3) received a single session of 18 min 1 Hz rTMS at 90% resting motor threshold intensity using an established coil positioning method targeting the Heschl's area of the left superior temporal gyrus. Standard pure tone audiometry and distortion-products otoacustic emissions (DPOAE) were performed before and immediately after stimulation. The main finding was that one session of 1 Hz rTMS over the temporal cortex modified neither the auditory threshold meaningfully nor the presence of DPOAE in healthy subjects. In conclusion, we found in this pilot approach no obvious indication for auditory dysfunctions due to direct electromagnetic stimulation of the superior temporal gyrus after one session of rTMS in healthy controls that may be interpreted as unwanted side effects. Nevertheless monitoring of auditory functions is strongly recommended in future clinical trials stimulating the auditory cortex, as this has not been done systematically in the past.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PRODUCT OTOACOUSTIC EMISSIONS; REPORTING HALLUCINATED VOICES; CHRONIC TINNITUS; MOTOR CORTEX; HEARING-LOSS; TEMPOROPARIETAL CORTEX; FOLLOW-UP; RTMS; EXCITABILITY; SCHIZOPHRENIA; Slow frequency transcranial magnetic stimulation; Functional interference; Biological treatment; Long term depression; Temporal cortex |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 May 2020 05:23 |
| Last Modified: | 12 May 2020 05:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18552 |
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