Kudielka, Brigitte M. and Gierens, Andrea and Hellhammer, Dirk H. and Wuest, Stefan and Schlotz, Wolff (2012) Salivary Cortisol in Ambulatory Assessment-Some Dos, Some Don'ts, and Some Open Questions. PSYCHOSOMATIC MEDICINE, 74 (4). pp. 418-431. ISSN 0033-3174, 1534-7796
Full text not available from this repository. (Request a copy)Abstract
The impact of stress on health and disease is an important research topic in psychosomatic medicine. Because research on hypothalamic-pituitary-adrenal (HPA) axis regulation under controlled laboratory studies lacks ecological validity, it needs to be complemented by a research program that includes momentary ambulatory assessment. The measurement of salivary cortisol offers the possibility to trace the free steroid hormone concentrations in ambulant settings. Therefore, in this article, we first discuss the role of salivary cortisol in ambulatory monitoring. We start with a brief description of HPA axis regulation, and we then consider cortisol assessments in other organic materials, followed by a presentation of common salivary markers of HPA axis regulation suitable for ambulatory assessment. We further provide an overview on assessment designs and sources of variability within and between subjects (intervening variables), acknowledge the issue of (non)compliance, and address statistical aspects. We further give an overview of associations with psychosocial and health-related variables relevant for ambulatory assessment. Finally, we deal with preanalytical aspects of laboratory salivary cortisol analysis. The relative simplicity of salivary cortisol assessment protocols may lead to an overoptimistic view of the robustness of this method. We thus discuss several important issues related to the collection and storage of saliva samples and present empirical data on the stability of salivary cortisol measurements over time.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PITUITARY-ADRENAL AXIS; ECOLOGICAL MOMENTARY ASSESSMENT; CHRONIC-FATIGUE-SYNDROME; POSTTRAUMATIC-STRESS-DISORDER; POPULATION-BASED SAMPLE; EFFORT-REWARD-IMBALANCE; MIDDLE-AGED MEN; AWAKENING RESPONSE; PERCEIVED STRESS; INDIVIDUAL-DIFFERENCES; ambulatory assessment; cortisol awakening response; HPA axis; laboratory cortisol analysis; salivary cortisol; stress |
| Subjects: | 100 Philosophy & psychology > 150 Psychology |
| Divisions: | Human Sciences > Institut für Psychologie Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie VII (Medizinische Psychologie, Psychologische Diagnostik und Methodenlehre) - Prof. Dr. Brigitte Kudielka |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 15 May 2020 05:48 |
| Last Modified: | 15 May 2020 05:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18804 |
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