Ortmann, Olaf and Lattrich, Claus (2012) The Treatment of Climacteric Symptoms. DEUTSCHES ARZTEBLATT INTERNATIONAL, 109 (17). 316-U38. ISSN 1866-0452,
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Background: Peri- and postmenopausal women commonly suffer from climacteric symptoms. In this article, we provide information to help physicians recognize climacteric symptoms and treat them appropriately. Methods: The information presented here is based on a selective search of the literature for pertinent articles that appeared from 2008 to early 2011, including the German S3 guideline on hormone therapy (HT) during and after menopause, which was published in 2009. Results: Perimenopausal women often suffer from climacteric symptoms. Typically, women undergoing menopause complain of heat waves and vaginal dryness. According to randomized controlled trials as well as national and international guidelines, HT is the most effective treatment for vasomotor symptoms and also improves vulvovaginal atrophy; for the latter indication, HT is preferably administered locally. Vaginal estrogen therapy lowers the frequency of recurrent urinary tract infections. However, HT is associated with an increased risk for a number of diseases, including stroke, thromboembolic events, gallbladder diseases, and breast cancer. Alternative treatments for climacteric symptoms have little or no efficacy. Conclusion: HT should only be used to treat climacteric symptoms after extensive patient education about its benefits and risks. Participatory decision-making is desirable. The generalized use of HT by all women with climacteric symptoms cannot be recommended.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HORMONE REPLACEMENT THERAPY; AMERICAN-MENOPAUSE-SOCIETY; RANDOMIZED CONTROLLED-TRIAL; POSTMENOPAUSAL WOMEN; POSITION STATEMENT; PROGESTOGEN USE; OVARIAN-CANCER; METAANALYSIS; ESTROGEN; RISK; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 May 2020 10:17 |
| Last Modified: | 14 May 2020 10:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18866 |
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