Wiggermann, P. and Jung, E. -M. and Gloeckner, S. and Hoffstetter, P. and Uller, W. and Vasilj, A. and Schreyer, A. and Stroszczynski, C. (2012) Real-Time Elastography of Hepatic Thermal Lesions In Vitro: Histopathological Correlation. ULTRASCHALL IN DER MEDIZIN, 33 (2). pp. 170-174. ISSN 0172-4614, 1438-8782
Full text not available from this repository. (Request a copy)Abstract
Purpose: To evaluate the reliability of elastography, a new ultrasonographic method, for delineating thermal lesion boundaries in porcine liver tissue by comparing lesion dimensions determined by real-time elastography with the findings at gross pathology. Materials and Methods: A total of 15 thermal lesions with diameters ranging from 17 to 60 mm were created using radiofrequency ablation (RFA). Color-coded elastography was performed by one experienced examiner, using a 6-15 MHz high frequency linear transducer (LOGIQ E9, GE). Lesions were examined using B-mode and real-time elastography (RTE). Lesion detection, delineation and size were assessed using B-mode and RTE immediately after each thermal ablation (<5 min). Measurements of the sections representing the same image plane used for elastography were taken during pathologic examination and compared to the measurements obtained from the elastograms. Results: In our sample a statistically significant correlation in vitro between RTE and pathological measurements with respect to the lesion's principal axis and area (r(2)=0.9338 long axis, r(2)=0.8998 short axis and r(2)=0.9676 area) was found. Overall, elastography slightly underestimated the lesion size, as judged by the digitalized pathologic images. Conclusion: These results support that RTE outperforms conventional B-mode ultrasound and could potentially be used for the routine assessment of thermal therapies.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GUIDED RADIOFREQUENCY ABLATION; FOCAL LIVER-LESIONS; HEPATOCELLULAR-CARCINOMA; TRANSIENT ELASTOGRAPHY; LOCAL RECURRENCE; SOFT-TISSUE; GUIDANCE; METASTASES; VOLUME; PROBE; abdomen; liver; radiofrequency (RF) ablation; technology assessment |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 15 May 2020 05:21 |
| Last Modified: | 15 May 2020 05:21 |
| URI: | https://pred.uni-regensburg.de/id/eprint/18912 |
Actions (login required)
 |
View Item |
