Erbas, Aykut and Horinek, Dominik and Netz, Roland R. (2012) Viscous Friction of Hydrogen-Bonded Matter. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134 (1). pp. 623-630. ISSN 0002-7863,
Full text not available from this repository. (Request a copy)Abstract
Amontons' law successfully describes friction between macroscopic solid bodies for a wide range of velocities and normal forces. For the diffusion and forced sliding of adhering or entangled macromolecules, proteins, and biological complexes, temperature effects are invariably important, and a similarly successful friction law at biological length and velocity scales is missing. Hydrogen bonds (HBs) are key to the specific binding of biomatter. Here we show that friction between hydrogen-bonded matter obeys in the biologically relevant low-velocity viscous regime a simple law: the friction force is proportional to the number of HBs, the sliding velocity, and a friction coefficient gamma(HB). This law is deduced from atomistic molecular dynamics simulations for short peptide chains that are laterally pulled over planar hydroxylated substrates in the presence of water and holds for widely different peptides, surface polarities, and applied normal forces. The value of gamma(HB) is extrapolated from simulations at sliding velocities in the range from V = 10(-2) to 100 m/s by mapping on a simple stochastic model and turns out to be of the order of gamma(HB) similar or equal to 10(-8) kg/s. The friction of a single HB thus amounts to the Stokes friction of a sphere with an equivalent radius of roughly 1 mu m moving in water. Cooperativity is pronounced: roughly three HBs act collectively.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MOLECULAR-BONDS; STICK-SLIP; DIFFUSION; SURFACES; SCALE; SIMULATION; POLYMERS; PEPTIDE; RUPTURE; PACKAGE; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Dominik Horinek |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 May 2020 10:23 |
| Last Modified: | 20 May 2020 10:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/19373 |
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