Michaelis, Stefanie and Robelek, Rudolf and Wegener, Joachim (2012) Studying Cell-Surface Interactions In Vitro: A Survey of Experimental Approaches and Techniques. In: UNSPECIFIED Advances in Biochemical Engineering-Biotechnology,, 126 . SPRINGER-VERLAG BERLIN, BERLIN, pp. 33-66. ISBN 978-3-642-28282-9
Full text not available from this repository. (Request a copy)Abstract
A better understanding of the interactions of animal (or human) cells with in vitro surfaces is the key to the successful development, improvement and optimization of biomaterials for biomedical or biotechnological purposes. State-of-the-art experimental approaches and techniques are a prerequisite for further and deeper insights into the mechanisms and processes involved in cell-surface adhesion. This chapter provides a brief but not complete survey of optical, mechanical, electrochemical and acoustic devices that are currently used to study the structural and functional properties of the cell-surface junction. Each technique is introduced with respect to the underlying principles before example data are discussed. At the end of the chapter all techniques are compared in terms of their strengths, limitations and technical requirements.
| Item Type: | Book Section |
|---|---|
| Uncontrolled Keywords: | QUARTZ-CRYSTAL MICROBALANCE; INTERFERENCE-CONTRAST MICROSCOPY; SHEAR-WAVE RESONATORS; PLASMON RESONANCE; MAMMALIAN-CELLS; LIVING CELLS; SUBSTRATE INTERACTIONS; REFLECTION MICROSCOPY; EXTRACELLULAR-MATRIX; OXIDIZED SILICON; Cell-surface interactions; Cell-surface junction; Cell adhesion; Cell migration; Cell spreading; Electric cell-substrate impedance sensing; Micromotion; Surface plasmon resonance; Quartz crystal microbalance |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Bioanalytik und Biosensorik (Prof. Joachim Wegener) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Jul 2020 09:38 |
| Last Modified: | 22 Jul 2020 09:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/19383 |
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