Cathodal stimulation of human MT+ leads to elevated fMRI signal: A tDCS-fMRI study

Antal, Andrea and Kovacs, Gyula and Chaieb, Leila and Cziraki, Csaba and Paulus, Walter and Greenlee, Mark W. (2012) Cathodal stimulation of human MT+ leads to elevated fMRI signal: A tDCS-fMRI study. RESTORATIVE NEUROLOGY AND NEUROSCIENCE, 30 (3). pp. 255-263. ISSN 0922-6028, 1878-3627

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Abstract

Purpose: Transcranial direct current stimulation (tDCS) was reintroduced about a decade ago as a tool for inducing long-lasting changes in cortical excitability. Recently it has been shown that both motor and cognitive functions can be influenced by tDCS. Here, we tested the effect of tDCS on the blood-oxygen level dependent (BOLD) signal evoked by coherent visual motion using functional magnetic resonance imaging (fMRI). Methods: The subjects underwent 10 min of cathodal and sham tDCS, applied over the right MT+. Following stimulation, random dot kinomatograms (RDK) with different percentages (10%, 30%, 50%) of coherently moving dots were presented. Results: All motion stimuli activated MT+ in both stimulation conditions. However, cathodal stimulation led to an increase in fMRI signal in MT+ when compared to sham stimulation. This effect did not depend on the coherence level of the visual stimulus. Conclusions: Here, we show for the first time, that cathodal tDCS stimulation leads to elevated fMRI signal in the human visual cortex.

Item Type: Article
Uncontrolled Keywords: TRANSCRANIAL MAGNETIC STIMULATION; NONINVASIVE BRAIN-STIMULATION; HUMAN MOTOR CORTEX; MOTION PERCEPTION; NEURONAL-ACTIVITY; DC-STIMULATION; ACTIVATION; TMS; EXCITABILITY; ADAPTATION; Area MT; fMRI; motion perception; transcranial direct current stimulation (tDCS)
Subjects: 100 Philosophy & psychology > 150 Psychology
Divisions: Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie I (Allgemeine Psychologie I und Methodenlehre) - Prof. Dr. Mark W. Greenlee
Depositing User: Dr. Gernot Deinzer
Date Deposited: 25 May 2020 06:55
Last Modified: 25 May 2020 06:55
URI: https://pred.uni-regensburg.de/id/eprint/19490

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