Prospective Registry On Mesothelioma Peritonei Treatment (PROMPT): study design and rationale

Cao, Christopher and Yan, Tristan D. and Morris, David L. and van der Speeten, Kurt and Laurberg, Soren and Glehen, Olivier and Link, Karl and Piso, Pompiliu and Tentes, Antonios-Apostolos K. and Deraco, Marcello and Larsen, Stein G. and Kecmanovic, Dragutin and Bayon, Luis G. and Melero, Juan T. and Gonzalez-Moreno, Santiago and Mahteme, Haile and Gertsch, Philippe and Moran, Brendan and Esquivel, Jesus and Alexander, Richard and Levine, Edward A. and Sugarbaker, Paul H. (2012) Prospective Registry On Mesothelioma Peritonei Treatment (PROMPT): study design and rationale. TUMORI, 98 (1). pp. 166-171. ISSN 0300-8916,

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Abstract

Diffuse malignant peritoneal mesothelioma (DMPM) is an aggressive and rare form of cancer arising from the mesothelial lining of the peritoneum. Due to the latency period between asbestos exposure and disease progression, the peak in incidence of DMPM is likely to occur in the coming decade for many industrialized nations, with a multitude of industrial, medico-legal and health-related implications(1,2). Traditional therapeutic modalities such as systemic chemotherapy and radiotherapy have not been proven to be effective in the treatment of DMPM, and patients diagnosed with the disease have a life expectancy of less than 12 months(3-5). Combined treatment involving cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been utilized in several specialized centers around the world and has been found to be a feasible procedure with encouraging survival outcomes(6-8).

Item Type: Article
Uncontrolled Keywords: INTRAPERITONEAL CHEMOTHERAPY; MALIGNANT MESOTHELIOMA; CYTOREDUCTIVE SURGERY; PROPENSITY SCORE; SURVIVAL; EFFICACY; BIAS; cytoreductive surgery; HIPEC; peritoneal mesothelioma; peritonectomy
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 25 May 2020 09:00
Last Modified: 25 May 2020 09:00
URI: https://pred.uni-regensburg.de/id/eprint/19515

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