Geis, Sebastian and Gehmert, S. and Lamby, P. and Zellner, J. and Pfeifer, C. and Prantl, L. and Jung, E. M. (2012) Contrast enhanced ultrasound (CEUS) and time intensity curve (TIC) analysis in compartment syndrome: First results. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 50 (1-2). pp. 1-11. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
Objective: Purpose of this study was to monitor changes of microcirculation in acute compartment syndrome using contrast enhanced ultrasound (CEUS) and to assess the modified perfusion with a special quantification software. Methods: 8 patients with trauma of the lower limb or the upper extremity were enrolled after acute compartment syndrome was diagnosed clinically and by intracompartmental pressure measurement. The qualitative analysis of the corresponding compartment was assessed using B-scan mode and CEUS simultaneously. CEUS was performed using a multifrequence probe (6-9 MHz, LOGIQ E9 GE) after a i.v. bolus injection of 2 x 2.4 ml contrast agent (SonoVue (R), Bracco, Italy). Digital raw data were stored as cine loops up to 2 minutes. Retrospectively semiquantitative perfusion analysis was performed using time intensity curve analysis and the quantification software QONTRAST (R). Results: 6 out of 8 patients had to be operated due to clinical symptoms and to a pressure perfusion gradient lower than 30 mm Hg. 2 out of 8 were treated conservatively. In all patients haematomas were seen in B-scan mode. No necrosis could be detected. In the TIC analysis low levels of time to peak (20.0+/-12.1) and area under the curve (118.4+/-87.8) were observed in acute compartment syndrome. Similarly results have been obtained using the perfusions parameter PEAK (11.1+/-5.7), time to PEAK (14.7+/-9.7), regional blood volume (257.1+/-192.6), and regional blood flow (12.1+/-6.5) in QONTRAST (R) perfusion software. Conclusion: CEUS may be capable of differing between acute compartment syndrome and imminent compartment syndrome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEAR-INFRARED SPECTROSCOPY; HIGH-RESOLUTION ULTRASOUND; HARMONIC IMAGING CHI; TRANSCUTANEOUS MONITORING TECHNIQUE; BOWEL WALL VASCULARIZATION; HEPATOCELLULAR-CARCINOMA; CROHNS-DISEASE; QUANTITATIVE ASSESSMENT; CAPILLARY RECRUITMENT; PERFUSION ANALYSIS; Trauma surgery; acute compartment syndrome; compartment monitoring; contrast enhanced ultrasound; tissue perfusion |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 25 May 2020 09:57 |
| Last Modified: | 25 May 2020 09:57 |
| URI: | https://pred.uni-regensburg.de/id/eprint/19521 |
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