Meier, J. K. and Prantl, Lukas and Mueller, S. and Moralis, A. and Liebsch, G. and Gosau, M. (2012) Simple, fast and reliable perfusion monitoring of microvascular flaps. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 50 (1-2). pp. 13-24. ISSN 1386-0291,
Full text not available from this repository. (Request a copy)Abstract
Background: Free tissue transfer in head and neck reconstructions has a very high success rate, but thrombotic vessel occlusion is still a serious complication occurring in up to 10% of all cases. Thus, a simple, fast and reliable monitoring system for free flaps would be of advantage. Objective: The aim of this study was to investigate whether free flap monitoring by measuring perfusion-dependent parameters is a suitable method for discovering vessel thrombosis in free flaps. Methods: 10 patients requiring tissue reconstruction after tumour surgery or because of chronic wounds were included in this study. 10 microvascular flaps were harvested and transplanted. Perfusion was determined by measuring a fluorescent oxygen sensor foil covering the flap's skin surface by means of a USB-handheld fluorescence microscope prototype. The sensor contained an oxygen reservoir which was consumed by the tissue corresponding to the perfusion status of the flap. Measurements were done before explantation, after successful anastomosis and 1 day after surgery. Results: Clinically well-perfused grafts showed slope values between 0.07 and 0.27 (mean: 0.18+/-0.07), and clinically poorly perfused grafts showed slope values between 0.35 and 0.75 (mean: 0.52+/-0.19). In the present study, we used a threshold slope value of 0.3 for differentiating between well-perfused and poorly perfused flaps. Conclusion: Flap monitoring via oxygen imaging by means of fluorescent sensor foils appears to be a fast, non-invasive, cost-effective and thus suitable method for analyzing flap perfusion with the additional advantage of aiding decision making on flap revision.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FREE-TISSUE TRANSFER; NECK RECONSTRUCTION; OXYGEN SENSORS; IN-VIVO; HEAD; COMPLICATIONS; THROMBOSIS; SALVAGE; FLUX; Free flap; microvascular; pO(2) imaging; fluorescent optical sensor |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 25 May 2020 10:05 |
| Last Modified: | 25 May 2020 10:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/19522 |
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