Kohl, Elisabeth A. and Karrer, S. (2011) Photodynamic therapy for photorejuvenation and non-oncologic indications: overview and update. GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA, 146 (6). pp. 473-485. ISSN 0392-0488, 1827-1820
Full text not available from this repository. (Request a copy)Abstract
Topical photodynamic therapy (PDT) has shown to be effective in the treatment and prevention of non-melanoma skin cancer. PDT is also established as treatment modality for several non-oncologic indications. The aesthetic effects of PDT for photoaged skin are well documented. An improvement of lentigines, skin roughness, sallow complexion and fine wrinkles was demonstrated. A reduction of histological signs of photoaging as a decrease of elastotic material and expression of p53 together with induction of neocollagenesis was shown. The possible contemporaneous treatment of non-melanoma skin cancer renders PDT a novel and effective technique for skin rejuvenation. Controlled studies also demonstrated the efficacy of PDT in the treatment of acne vulgaris and HPV-induced skin diseases as verrucae vulgares and condylomata acuminata. In addition, there is evidence that certain sclerosing, inflammatory, granulomatous and infectious skin diseases may profit from PDT. In contrast to PDT of tumours, where cellular destruction is the main goal of the therapy, in PDT of inflammatory skin conditions it is probably the modulation of cellular functions that plays the main role.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TOPICAL 5-AMINOLEVULINIC ACID; INTENSE PULSED-LIGHT; RANDOMIZED CLINICAL-TRIAL; VULVAR LICHEN-SCLEROSUS; DELTA-AMINOLEVULINIC-ACID; FACIAL ACNE-VULGARIS; METHYL AMINOLEVULINATE; CONDYLOMATA ACUMINATA; DYE-LASER; VIRAL WARTS; Skin aging; Photochemotherapy; Warts; Acne vulgaris; Scleroderma, localized; Leishmaniasis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 May 2020 08:55 |
| Last Modified: | 26 May 2020 08:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/19740 |
Actions (login required)
 |
View Item |
