Scherer, Max and Boettcher, Alfred and Liebisch, Gerhard (2011) Lipid profiling of lipoproteins by electrospray ionization tandem mass spectrometry. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1811 (11). pp. 918-924. ISSN 1388-1981, 0006-3002
Full text not available from this repository. (Request a copy)Abstract
Lipoproteins are of fundamental importance for the lipid transport and cardiovascular disease. The function and metabolism of lipoproteins is intimately linked to the biophysical properties of their surface lipids. Although a number of disease associations were found for lipid species in plasma, only a few studies reported lipid profiles of lipoproteins. Here, we provide an overview of techniques for lipoprotein separation, methods for lipid species analysis based on electrospray ionization tandem mass spectrometry (ESI-MS/MS) as well as data from recent lipidomic studies on lipoprotein fractions. We also discuss the different analytical strategies and how lipid profiling can expand our understanding of the biology and structures of lipoproteins. This article is part of a Special Issue entitled Lipodomics and Imaging Mass Spectrometry. (C) 2011 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LECITHIN-CHOLESTEROL ACYLTRANSFERASE; HIGH-THROUGHPUT QUANTIFICATION; LOW-DENSITY LIPOPROTEINS; CELLULAR FREE-CHOLESTEROL; QUANTITATIVE-ANALYSIS; PLASMA-LIPOPROTEINS; HUMAN-SERUM; ELECTROPHORETIC SEPARATION; SPHINGOSINE 1-PHOSPHATE; INCREASED SPHINGOMYELIN; Lipoprotein separation; Lipidomics; Phospholipids; Sphingolipids; Lipid species |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Petra Gürster |
| Date Deposited: | 06 May 2020 10:16 |
| Last Modified: | 06 May 2020 10:16 |
| URI: | https://pred.uni-regensburg.de/id/eprint/19852 |
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