Neonatal outcome using ultrathin fetoscope for laser coagulation in twin-to-twin-transfusion syndrome

Tchirikov, Michael and Oshovskyy, Viktor and Steetskamp, Joscha and Falkert, Andreas and Huber, Georgine and Entezami, Michael (2011) Neonatal outcome using ultrathin fetoscope for laser coagulation in twin-to-twin-transfusion syndrome. JOURNAL OF PERINATAL MEDICINE, 39 (6). pp. 725-730. ISSN 0300-5577,

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Abstract

Objective: To improve neonatal outcome using ultrathin fetoscope for laser treatment of twin-to-twin transfusion syndrome. Methods: Retrospective cohort study of a series of 80 cases of twin-to-twin-transfusion syndrome prior to 26 weeks' gestation subjected to laser coagulation by means of a 1.0/1.2 mm fiber fetoscope with a sheath sectional area 2.65 mm(2)/3.34 mm(2) (n=27) and a 2.0 mm classic lens fetoscope with a sheath sectional area: 6.63 mm(2)/11.27 mm(2) (n=53). Results: The survival rates of at least one twin in the compared groups were 94.4% (classic optic) and 100% (ultrathin optic), for both twins: 75.5% and 83.3%, respectively. By decreasing sheath diameter a pregnancy was prolonged by an average of 21.3 days (P=0.0045), with a resulting increase in the recipient's weight of 389 g (P=0.0049) and an increase in the donor's Apgar score. However, the intervention with ultrathin optic took 11 min longer (P=0.031). Conclusion: The reduction of the iatrogenic damage of the amniotic membrane using ultrathin fetoscope with a small sheath, significantly improves the neonatal outcome after laser treatment of twin-to-twin-transfusion syndrome. The operator should only commence working with the 1 mm fetoscope after the learning curve has been accomplished.

Item Type: Article
Uncontrolled Keywords: FETAL SURGERY; TRACHEAL OCCLUSION; PREMATURE RUPTURE; MEMBRANES; PHOTOCOAGULATION; EXPERIENCE; MANAGEMENT; CELLS; 1.0 mm Fetoscope; laser coagulation; monochorionic pregnancy; neonatal outcome; twin-to-twin transfusion syndrome
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 27 May 2020 09:46
Last Modified: 27 May 2020 09:46
URI: https://pred.uni-regensburg.de/id/eprint/19906

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