The enlightenment of bladder cancer treatment: origin and progress of photodynamic diagnosis

Otto, Wolfgang and Burger, Maximilian and Fritsche, Hans-Martin and Roessler, Wolfgang and Wieland, Wolf F. and Denzinger, Stefan (2011) The enlightenment of bladder cancer treatment: origin and progress of photodynamic diagnosis. FUTURE ONCOLOGY, 7 (9). pp. 1057-1066. ISSN 1479-6694

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Abstract

Compared with prostate cancer, which exclusively affects male patients, urothelial bladder cancer is the most common urogenital carcinoma affecting both men and women. In approximately 75% of cases, bladder cancer occurs as multifocal nonmuscle-invasive papillary tumor that demonstrates high rates of recurrence, leading to frequent transurethral resections with the need of hospitalization. These cases have paved the way for photodynamic diagnosis. Since the 1990s, this technique has been used to identify bladder tumors, especially highly aggressive carcinoma in situ, in an easier and more complete way compared with conventional white-light cystoscopy. This article gives an up-to-date review of the method, indication and results of photodynamic diagnosis for treatment of urothelial bladder cancer.

Item Type: Article
Uncontrolled Keywords: INDUCED FLUORESCENCE DIAGNOSIS; CLINICALLY RELEVANT REDUCTION; 5-AMINOLEVULINIC ACID; TRANSURETHRAL RESECTION; UROTHELIAL CARCINOMA; FOLLOW-UP; EAU GUIDELINES; PHASE-III; RECURRENCE; RISK; bladder cancer; fluorescence cystoscopy; hexaminolevulinate acid; photodynamic diagnosis; recurrence-free survival; transurethral resection; urothelial carcinoma
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Urologie
Depositing User: Petra Gürster
Date Deposited: 05 May 2020 06:52
Last Modified: 05 May 2020 06:52
URI: https://pred.uni-regensburg.de/id/eprint/20224

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