Hautmann, Anke Heidewig and Elad, Sharon and Lawitschka, Anita and Greinix, Hildegard and Bertz, Hartmut and Halter, Joerg and Faraci, Maura and Hofbauer, Lorenz Christian and Lee, Stephanie and Wolff, Daniel and Holler, Ernst (2011) Metabolic bone diseases in patients after allogeneic hematopoietic stem cell transplantation: Report from the Consensus Conference on Clinical Practice in chronic graft-versus-host disease. TRANSPLANT INTERNATIONAL, 24 (9). pp. 867-879. ISSN 0934-0874, 1432-2277
Full text not available from this repository. (Request a copy)Abstract
With improved outcome of allogeneic stem cell transplantation (allo-SCT) for hematologic malignancies, long-term complications gain greater importance. Skeletal complications such as osteoporosis or avascular necrosis (AVN) occur frequently in allogeneic recipients with a cumulative incidence of diminished bone mineral density of 24-50% between 2 and 12 months after allo-SCT and a cumulative incidence of AVN in as many as 19% of patients 3 years after allo-SCT. Here, we present a review as part of the German, Austrian, and Swiss Consensus Conference on clinical practice in chronic graft-versus-host disease, held 2009 in Regensburg. The Consensus Conference aimed to achieve a consensus on the current evidence of diagnosis, prevention, and therapeutic options of late complications after allo-SCT summarizing and discussing the literature on these topics. In this report, we provide recommendations for metabolic bone diseases agreed upon by the working party. This includes guidelines for diagnosis, prevention, and therapeutic options in patients with low bone mass or AVN.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LONG-TERM SURVIVORS; ACUTE LYMPHOBLASTIC-LEUKEMIA; MESENCHYMAL STROMAL CELLS; VITAMIN-D DEFICIENCY; MARROW-TRANSPLANTATION; AVASCULAR NECROSIS; MINERAL DENSITY; ZOLEDRONIC ACID; RISK-FACTORS; BISPHOSPHONATE THERAPY; allogeneic hematopoietic stem cell transplantation; avascular necrosis; bisphosphonates; bone marrow transplantation; malignancies and long-term complications; osteoporosis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 04 May 2020 08:50 |
| Last Modified: | 04 May 2020 08:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/20372 |
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