OCT in Macular Diagnostics - Possibilities and Limitations

Gamulescu, M. A. and Helbig, H. (2011) OCT in Macular Diagnostics - Possibilities and Limitations. KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 228 (7). pp. 599-606. ISSN 0023-2165, 1439-3999

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Abstract

During the last years, optical coherence tomography (OCT) has evolved to an important diagnostic tool in ophthalmology. In addition to ophthalmoscopy and the topographic visualisation of pathologies of the posterior part of the eye by fluorescein and indocyanine-green angiography, OCT adds complementary tomographic information on the retinal structures. First generation (time domain) OCT machines already generated pictures that resemble histological cross-sections of the retina. With the new OCTs of the spectral/frequency/Fourier domain generation, topographic and tomographic information can be presented side-by-side or in combination, thereby increasing the accuracy of the localisation of the visualised structures. Because of its non-invasive methodology without contact to the patient's eye and the faster acquisition times with increasing resolution, the OCT has become a valuable instrument in the modern anatomic and structural diagnostics of the macula. Functional statements are not yet possible in a comprehensive manner, but first steps have been made with the interpretation of structural information from high-resolution images. In this paper, the emerging possibilities from a widespread use of the OCT, as well as the limitations of this diagnostic technique, are discussed.

Item Type: Article
Uncontrolled Keywords: OPTICAL COHERENCE TOMOGRAPHY; SUBRETINAL NEOVASCULARIZATION; INTRAVITREAL RANIBIZUMAB; FLUORESCEIN ANGIOGRAPHY; VISUAL-ACUITY; EDEMA; BEVACIZUMAB; RESOLUTION; DEGENERATION; INTEGRITY; optical coherence tomography; time domain; frequency domain; Retina; structure; visualisation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Depositing User: Petra Gürster
Date Deposited: 30 Apr 2020 08:59
Last Modified: 30 Apr 2020 08:59
URI: https://pred.uni-regensburg.de/id/eprint/20597

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