First application of a new portable, miniaturized system for extracorporeal membrane oxygenation

Mueller, Thomas and Philipp, A. and Lubnow, M. and Weingart, C. and Pfeifer, M. and Riegger, G. A. J. and Schmid, C. (2011) First application of a new portable, miniaturized system for extracorporeal membrane oxygenation. PERFUSION-UK, 26 (4). pp. 284-288. ISSN 0267-6591,

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Abstract

Extracorporeal assist systems for respiratory and circulatory failure are increasingly used in intensive care medicine. Important technical innovations over the past years have resulted in improved biocompatibility and, consequently, reduced complication rates. Extracorporeal membrane oxygenation (ECMO) technology experienced a surge of use during the influenza A (H1N1) pandemic, but transport of unstable patients with life-threatening ARDS is still hazardous. We describe the first successful application of a newly developed, compact and easily portable ECMO device in a patient with severe ARDS due to influenza A (H1N1). Support with the miniaturized ECMO resulted in immediate improvement of gas exchange and a highly protective ventilation. Inspiratory pressure was decreased from 40 to 29 cmH(2)O and tidal volume per kilogram of predicted bodyweight could be reduced from 6.5 to 3.3 mL. Small and efficient heart-lung assist systems will become a tool of growing importance in intensive care medicine, both for profound respiratory and cardiac failure in the future. The reduced weight and compact design of the device greatly facilitates transport and handling of unstable patients on ECMO.

Item Type: Article
Uncontrolled Keywords: RESPIRATORY-DISTRESS-SYNDROME; FAILURE; SHOCK; LIFE; miniaturized extracorporeal membrane oxygenation; acute respiratory distress syndrome; swine flu; protective ventilation; CardioHelp
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Jun 2020 11:18
Last Modified: 08 Jun 2020 11:18
URI: https://pred.uni-regensburg.de/id/eprint/20598

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