Marks, C. and Stadler, M. and Haeusermann, P. and Wolff, D. and Buchholz, S. and Stary, G. and Lee, S. and Lawitschka, A. and Bertz, H. (2011) German-Austrian-Swiss Consensus Conference on clinical practice in chronic graft-versus-host disease (GVHD): guidance for supportive therapy of chronic cutaneous and musculoskeletal GVHD. BRITISH JOURNAL OF DERMATOLOGY, 165 (1). pp. 18-29. ISSN 0007-0963
Full text not available from this repository. (Request a copy)Abstract
Supportive therapy plays a central role in the management of cutaneous and musculoskeletal manifestations of chronic graft-versus-host disease (cGVHD), either alone or in combination with systemic approaches. We present results from the German-Austrian-Swiss Consensus Conference on clinical practice in cGVHD, held in Regensburg, Germany, in November 2009. The intention was to achieve a consensus on current evidence-based treatment options as well as to provide guidelines for daily clinical practice. Skin is the most common organ involved in cGVHD. Its clinical presentation varies considerably. Patients may have pruritus, rash, pain, dyspigmentation and fibrotic or sclerodermatous lesions, often leading to contractures. Treatment options for supportive therapy in cutaneous cGVHD include topical therapies such as topical steroids and topical calcineurin inhibitors, as well as phototherapy and physiotherapy. The most relevant manifestation in musculoskeletal cGVHD is fasciitis which must be distinguished from sclerodermatous skin cGVHD. Physiotherapy is the mainstay of supportive treatment in fasciitis in cGVHD. Successful therapy of cutaneous and musculoskeletal cGVHD depends on interdisciplinary management to improve patients' quality of life.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | STEM-CELL TRANSPLANTATION; BONE-MARROW-TRANSPLANTATION; WORKING GROUP-REPORT; REFRACTORY CHRONIC GVHD; QUALITY-OF-LIFE; EXTRACORPOREAL PHOTOCHEMOTHERAPY; DEVELOPMENT PROJECT; BATH PHOTOCHEMOTHERAPY; EOSINOPHILIC FASCIITIS; ULTRAVIOLET-RADIATION; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 30 Apr 2020 10:38 |
| Last Modified: | 30 Apr 2020 10:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/20610 |
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