Experience with non-ablative fractional photothermolysis with a dual-mode laser device (1,440/1,320 nm): no considerable clinical effect on hypertrophic/acne scars and facial wrinkles

Babilas, Philipp and Schreml, Stephan and Eames, Tatiana and Hohenleutner, Ulrich and Landthaler, Michael and Hohenleutner, Silvia (2011) Experience with non-ablative fractional photothermolysis with a dual-mode laser device (1,440/1,320 nm): no considerable clinical effect on hypertrophic/acne scars and facial wrinkles. LASERS IN MEDICAL SCIENCE, 26 (4). pp. 473-479. ISSN 0268-8921,

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Abstract

In the literature, non-ablative fractionated photothermolysis (nFP) is accredited with improvement of wrinkles and scars combined with a reduced downtime. The purpose of this work was to evaluate the impact of a combination laser (1,320/1,440 nm) for nFP on hypertrophic scars, acne scars, and facial wrinkles. Thirty-six patients suffering from hypertrophic scars (n = 7), acne scars (n = 9), and wrinkles (n = 20) were treated using a combination Nd:YAG laser [lambda(em) = 1,320 and 1,440 nm, pulse duration: 3-ms single pulse, fluence: 8.0-9.0 J/cm(2) (1,320 nm); 2.0-2.5 J/cm(2) (1,440 nm)]. The appearance of the treated condition was evaluated in a retrospective study by two blinded investigators based on follow-up photographs and by patient self-assessment. The frequency of side-effects was also assessed. Both patients and blinded observers rated the treatment results for hypertrophic scars and acne scars as slight improvement, and for wrinkles as equal as compared to baseline. No serious side-effects were reported. The light device used did not lead to a considerable clinical improvement of hypertrophic scars, acne scars, or wrinkles in this study.

Item Type: Article
Uncontrolled Keywords: ND-YAG LASER; PULSED DYE; SKIN; PHOTOREJUVENATION; REDUCTION; EFFICACY; THERAPY; RHYTIDS; TRIAL; Affirm; Fraxel; Scars; Wrinkles; Neodymium: YAG; Laser
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 09 Jun 2020 05:47
Last Modified: 09 Jun 2020 05:47
URI: https://pred.uni-regensburg.de/id/eprint/20619

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